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货号: bs-8473R-FITC 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-8473R-FITC
- 英文名称
- Anti-FBXL20/FITC
- 中文名称
- FITC标记的FBXL20蛋白抗体
- 别 名
- F box/LRR repeat protein 20; F box/LRR repeat protein 2 like; F box/LRR repeat protein 20; Fbl2; Fbl20; F box and leucine rich repeat protein 20; MGC15482; SCR; SCRAPPER; FXL20_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 48kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FBXL20
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission.
Subunit:
Interacts with SKP1 and CUL1.
Subcellular Location:
Cytoplasmic.
Similarity:
Contains 1 F-box domain.
Contains 13 LRR (leucine-rich) repeats.
Database links:Entrez Gene: 84961 Human
Entrez Gene: 72194 Mouse
Entrez Gene: 64039 Rat
SwissProt: Q96IG2 Human
SwissProt: Q9CZV8 Mouse
SwissProt: Q9QZH7 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.