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货号： bs-9056R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9056R-FITC
- 英文名称
- Anti-Dermokine beta/FITC
- 中文名称
- FITC标记的Dermokine β蛋白抗体
- 别 名
- Dermokineβ; Dermokine-β; DMKN;Dermokine beta; Dermokine delta 1; Dermokine delta 5a; Dermokine delta 5b; Dermokine gamma 1; Dermokine gamma 2; UNQ729; ZD52F10 protein; Epidermis-specific secreted protein SK30/SK89; DMKN_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Rat,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 45kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Dermokine beta
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Dermokine, also known as DMKN, ZD52F10 or UNQ729, is a 476 amino acid secreted protein that belongs to the dermokine family and exists as 15 alternatively spliced isoforms, the most notable of which are designated å and ∫. Existing as a homooligomer that can either homodimerize or homotrimerize, Dermokine is expressed in the epidermis, as well as in the epithelia of the lung and small intestine where it is thought to function as a regulator of keratinocyte differentiation, possibly playing a role in inflammatory responses. The gene encoding Dermokine maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
Function:
May act as a soluble regulator of keratinocyte differentiation (Potential).
Subunit:
Homooligomer. Seems to be able to homodimerize and homotrimerize.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed in epidermis; in the spinous and granular layers and in placenta. Also found in the epithelia of the small intestine, macrophages of the lung and endothelial cells of the lung. Isoform 15 is expressed in epidermis and placenta. Isoform 1 is expressed in epidermis.
Post-translational modifications:
O-glycosylated.
Similarity:
Belongs to the dermokine family.
Database links:Entrez Gene: 93099Human
SwissProt: Q6E0U4Human
SwissProt: Q96EW8Human
Unigene: 417795Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.