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货号： bs-4835R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4835R-FITC
- 英文名称
- Anti-MAL/FITC
- 中文名称
- FITC标记的MAL蛋白抗体
- 别 名
- MAL; mal; MAL protein gene; Mal T-cell differentiation protein; MAL_HUMAN; MALGENE; MPV17; Myelin and lymphocyte protein; T-cell differentiation protein MAL; T-lymphocyte maturation-associated protein; VIP17.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 细胞凋亡 细胞周期蛋白 细胞分化
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Rat,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 17kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MAL/MPV17
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
MAL (myelin and lymphocyte protein), also known as T lymphocyte maturation-associated protein, is a nonglycosylated hydrophobic integral membrane protein belonging to the Myelin and lymphocyte (MAL) family of proteolipids. MAL is highly enriched in nervous system myelin and in rafts and apical membranes of epithelial cells. It is involved in forming, stabilizing and maintaining glycosphingolipid-enriched membrane microdomains. MAL maintains the myelin sheath and, by controlling the sorting and trafficking of oligodendrocytes, it is involved in central nervous system paranode maintenance. MAL is a component of lipid rafts in myelinating cells. Association with glycosphingolipids may result in protein-lipid microdomain formation in myelin. MAL has been localized to the endoplasmic reticulum of T cells and in compact myelin of cells in the nervous system. MAL is primarily expressed by oligodendrocytes and Schwann cells in the intermediate and late stages of T cell differentiation.
Function:
Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Post-translational modifications:
Lipoprotein.
Similarity:
Belongs to the MAL family.
Contains 1 MARVEL domain.
Database links:Entrez Gene: 4118 Human
Entrez Gene: 17153 Mouse
Entrez Gene: 25263 Rat
Omim: 188860 Human
SwissProt: Q28296 Dog
SwissProt: P21145 Human
SwissProt: O09198 Mouse
SwissProt: Q64349 Rat
Unigene: 80395 Human
Unigene: 39040 Mouse
Unigene: 10174 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.