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货号： bs-9927R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9927R-FITC
- 英文名称
- Anti-GALR1/FITC
- 中文名称
- FITC标记的甘丙肽受体1抗体
- 别 名
- GAL1R; galanin receptor 1; Galanin receptor; Galanin receptor type 1; GALNR; GALNR1; GALR1; GALR1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 神经生物学 信号转导 生长因子和激素 通道蛋白 G蛋白偶联受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 39kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GALR1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
GALR1 is a G-protein-coupled receptor for the neuropeptide galanin that influences endocrine secretions, intestinal motility, memory, weight, and pain perception. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, and in peripheral sites such as the small intestine and heart. The rat galanin receptor cDNA cloned from an insulinoma cell line is a predicted 346-amino acid G protein-coupled receptor with 92% homology to the human GALR1.
Function:
Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
Subcellular Location:
Cell Membrane; multi pass membrane protein
Post-translational modifications:
Palmitoylated on at least one of the three cysteine residues present in the C-terminal part.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:Entrez Gene: 2587 Human
Entrez Gene: 14427 Mouse
Omim: 600377 Human
SwissProt: P47211 Human
SwissProt: P56479 Mouse
Unigene: 272191 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.