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货号： bs-11327R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11327R-FITC
- 英文名称
- Anti-PTP zeta/FITC
- 中文名称
- FITC标记的磷酸蛋白聚糖PTPRZ抗体
- 别 名
- Phosphacan; 3F8 chondroitin sulfate proteoglycan; 3H1 keratan sulfate proteoglycan; HPTPZ; HPTPzeta; Phosphacan; Protein tyrosine phosphatase receptor type Z polypeptide 2; Protein tyrosine phosphatase, receptor type, Z polypeptide 1; Protein tyrosine phosphatase, receptor type, zeta polypeptide 1; PTP-ZETA; PTP18; PTPRZ; PTPRZ1; PTPZ; R PTP zeta 2; R-PTP-zeta; Receptor type tyrosine phosphatase beta/zeta; Receptor-type tyrosine-protein phosphatase zeta; RPTP-BETA; RPTPB; RPTPbeta; PTPRZ_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 激酶和磷酸酶 细胞类型标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 251kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Phosphacan
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
PTP zeta (receptor-type protein tyrosine phosphatase zeta) is a type I membrane protein chondroitin sulfate proteoglycan with a transmembrane domain and intracellular tyrosine phosphatase domains. PTP zeta may be involved in the regulation of specific developmental processes in the CNS. PTP zeta is developmentally regulated in the brain and specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. PTP zeta belongs to the protein-tyrosine phosphatase family and contains 1 eukaryotic-type carbonic anhydrase domain, 1 fibronectin type III domain and 2 tyrosine-protein phosphatase domains.
Function:
May be involved in the regulation of specific developmental processes in the CNS.
Subunit:
The carbonic-anhydrase like domain binds to contactin (By similarity).
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain.
Similarity:
Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
Contains 1 alpha-carbonic anhydrase domain.
Contains 1 fibronectin type-III domain.
Contains 2 tyrosine-protein phosphatase domains.
Database links:Entrez Gene: 5803Human
Entrez Gene: 19283Mouse
Entrez Gene: 25613Rat
Omim: 176891Human
SwissProt: P23471Human
SwissProt: Q62656Rat
Unigene: 489824Human
Unigene: 10088Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.