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货号： bsm-30080M-FITC-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bsm-30080M-FITC-AP
- 英文名称
- Anti-human CD38-FITC/AP
- 中文名称
- 碱性磷酸酶（AP）标记的FITC标记小鼠抗人CD38单克隆抗体
- 别 名
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2-phospho-ADP-ribosyl cyclase; 2-phospho-ADP-ribosyl cyclase/2-phospho-cyclic-ADP-ribose transferase; 2-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADPRC 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10; CD38_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 干细胞 糖尿病 细胞表面分子 糖蛋白 淋巴细胞 t-淋巴细胞 b-淋巴细胞
- 抗体来源
- Mouse
- 克隆类型
- Monoclonal
- 交叉反应
- Human,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 34kDa
- 性 状
- Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein G
- 储 存 液
- Constituents: 0.05M TBS, pH 8.0 with 10mg/ml BSA and 0.05% NaN3, 50% glycerol. Or Lyophilized. Buffer = 0.05M TBS, pH 8.0 with 10mg/ml BSA and 0.05% NaN3. Reconstitute with sterile distilled water.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Function:
Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Subcellular Location:
Membrane; Single-pass type II membrane protein.
Tissue Specificity:
Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
Similarity:
Belongs to the ADP-ribosyl cyclase family.
Database links:Entrez Gene: 952 Human
Omim: 107270 Human
SwissProt: P28907 Human
Unigene: 479214 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.