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货号： bs-21285R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21285R-AP
- 英文名称
- Anti-RBM11/AP
- 中文名称
- 碱性磷酸酶（AP）标记的RNA结合蛋白11抗体
- 别 名
- Putative RNA binding protein 11; RNA binding motif protein 11; Splicing regulator RBM11.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 发育生物学 神经生物学 结合蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 32kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RBM11
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
RBM11, also known as RNA binding motif protein 11, is a human gene. 2 isoforms of the human protein are produced by alternative splicing.
Function:
Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5 splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1.
Subunit:
Homodimer.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain.
Similarity:
Contains 1 RRM (RNA recognition motif) domain.
Database links:Entrez Gene: 54033Human
Entrez Gene: 288321Rat
SwissProt: P57052Human
Unigene: 283828Human
Unigene: 154372Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.