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货号： bs-12896R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12896R-AP
- 英文名称
- Anti-TAF13/AP
- 中文名称
- 碱性磷酸酶（AP）标记的转录起始因子TFIID亚基13抗体
- 别 名
- MGC22425; TAF(II)18; taf13; TAF13 RNA polymerase II, TATA box binding protein (TBP) associated factor, 18kDa; TAF13_HUMAN; TAF2K; TAFII 18; TAFII-18; TAFII18; Transcription initiation factor TFIID 18 kDa subunit; Transcription initiation factor TFIID subunit 13.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Orangutan
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 14kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TAF13
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6. [provided by RefSeq, Jul 2008]
Function:
TFIID beta-specific TAFII.
Subunit:
TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Interacts with TBP, and more strongly with TAF10 and TAF11.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the TAF13 family.
Contains 1 histone-fold domain.
Database links:Entrez Gene: 513065Cow
Entrez Gene: 6884Human
Entrez Gene: 99730Mouse
Entrez Gene: 100172778Orangutan
Omim: 600774Human
SwissProt: Q148M7Cow
SwissProt: Q15543Human
SwissProt: P61216Mouse
SwissProt: Q5R9W6Orangutan
Unigene: 632426Human
Unigene: 24431Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.