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货号： bs-12641R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12641R-AP
- 英文名称
- Anti-SMPD4/AP
- 中文名称
- 碱性磷酸酶（AP）标记的鞘磷脂磷酸二酯酶4抗体
- 别 名
- EC 3.1.4.12; EC=3.1.4.123; FLJ20297; FLJ20756; KIAA1418; NET 13; NET13; Neutral sphingomyelinase 3; Neutral sphingomyelinase III; NSMA3_HUMAN; nSMase 3; nSMase-3; nSMase3; OTTHUMP00000162391; OTTHUMP00000190862; SKNY protein; smpd4; Sphingomyelin phosphodiesterase 4; Sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase 3).
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 转运蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 93kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SMPD4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Sphingomyelinases (EC 3.1.4.12), such as SMPD4, catalyze the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide (Krut et al., 2006 [PubMed 16517606]).[supplied by OMIM, Mar 2008]
Function:
Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide.
Subunit:
Associates with spliceosomes. Associates with U4/U5/U6 tri-snRNP and with U2 snRNP.
Subcellular Location:
Endoplasmic reticulum membrane. Golgi apparatus membrane.
Tissue Specificity:
Widely expressed, with highest levels in heart and skeletal muscle.
Similarity:
Belongs to the SMN family.Contains 1 Tudor domain.
Database links:Entrez Gene: 55627Human
Entrez Gene: 77626Mouse
Entrez Gene: 303790Rat
Omim: 610457Human
SwissProt: Q9NXE4Human
SwissProt: Q6ZPR5Mouse
Unigene: 516450Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.