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货号： bs-19970R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19970R-AP
- 英文名称
- Anti-PPP2R5A/AP
- 中文名称
- 碱性磷酸酶（AP）标记的蛋白磷酸酶2调节亚基5A抗体
- 别 名
- 2A5A_HUMAN; B56A; MGC131915; PP2A B subunit B alpha isoform; PP2A B subunit B56 alpha isoform; PP2A B subunit isoform B-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PP2A B subunit isoform R5-alpha; PP2A B subunit PR61 alpha isoform; PP2A B subunit R5 alpha isoform; PPP2R5A; PR61A; PR61alpha; Protein phosphatase 2 regulatory subunit B (B56) alpha isoform; Protein phosphatase 2 regulatory subunit B alpha isoform; Protein phosphatase 2 regulatory subunit B alpha; Serine/threonine protein phosphatase 2A 56kDa regulatory subunit alpha isoform; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 56kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PPP2R5A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Function:
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Subcellular Location:
Cytoplasm. Nucleus. Chromosome > centromere. From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase.
Tissue Specificity:
Widely expressed with the highest expression in heart and skeletal muscle.
Post-translational modifications:
Phosphorylated on serine residues.
Similarity:
Belongs to the phosphatase 2A regulatory subunit B56 family.
Database links:Entrez Gene: 5525Human
Entrez Gene: 226849Mouse
Entrez Gene: 312754Rat
Omim: 601643Human
SwissProt: Q15172Human
SwissProt: Q6PD03Mouse
Unigene: 497684Human
Unigene: 205569Mouse
Unigene: 104461Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.