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货号： bs-19932R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19932R-AP
- 英文名称
- Anti-TIMM50/AP
- 中文名称
- 碱性磷酸酶（AP）标记的线粒体内膜转位同源蛋白50抗体
- 别 名
- Homolog of yeast Tim50; Import inner membrane translocase subunit TIM 50; Import inner membrane translocase subunit TIM50; Import inner membrane translocase subunit TIM50 mitochondrial; MGC102733; Mitochondrial import inner membrane translocase subunit TIM50; TIM 50; TIM 50L; TIM50; Tim50 like protein; TIM50_HUMAN; TIM50L; TIMM 50; TIMM50; Translocase of inner mitochondrial membrane 50 homolog (yeast); Translocase of inner mitochondrial membrane 50 homolog.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 转运蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 35kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TIMM50
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.
Subunit:
Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50; within this complex, directly interacts with TIMM23. The complex interacts with the TIMM44 component of the PAM complex and with DNAJC15.
Subcellular Location:
Mitochondrion inner membrane and Nucleus speckle. Nuclear and enriched in speckles with snRNPs.
Tissue Specificity:
Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level).
Similarity:
Belongs to the TIM50 family.
Contains 1 FCP1 homology domain.
Database links:Entrez Gene: 92609Human
Entrez Gene: 66525Mouse
Entrez Gene: 685725Rat
Omim: 607381Human
SwissProt: Q3ZCQ8Human
SwissProt: Q9D880Mouse
Unigene: 590956Human
Unigene: 597106Human
Unigene: 167913Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.