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货号： bs-19911R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19911R-AP
- 英文名称
- Anti-PCDH19/AP
- 中文名称
- 碱性磷酸酶（AP）标记的原钙粘附蛋白19抗体
- 别 名
- KIAA1313; PCD19_HUMAN; PCDH19; Protocadherin 19; Protocadherin-19.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 细胞粘附分子 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 124kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PCDH19
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Defects in this gene are a cause of epilepsy female-restricted with mental retardation (EFMR). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
Function:
Potential calcium-dependent cell-adhesion protein.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Moderately expressed in all regions of the brain examined, with lowest levels found in the cerebellum. Moderate expression is also found in ovary, and low expression in all other tissues tested. Also detected in primary skin fibroblast.
DISEASE:
Epileptic encephalopathy, early infantile, 9
Similarity:
Contains 6 cadherin domains.
Database links:Entrez Gene: 57526Human
Entrez Gene: 101125719Gorilla
Entrez Gene: 100059478Horse
Entrez Gene: 279653Mouse
Omim: 300460Human
SwissProt: Q8TAB3Human
SwissProt: Q80TF3Mouse
Unigene: 4993Human
Unigene: 39738Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.