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货号： bs-19682R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19682R-AP
- 英文名称
- Anti-SFMBT1/AP
- 中文名称
- 碱性磷酸酶（AP）标记的SFMBT1蛋白抗体
- 别 名
- DKFZp434L243; MGC93349; OTTMUSP00000030378; OTTMUSP00000030379; OTTMUSP00000030381; Renal ubiquitous protein 1; RU1; Scm like with four mbt domains 1; Scm like with four MBT domains protein 1; Scm related gene containing four mbt domains; Scm related gene product containing four mbt domains; Scm-like with four MBT domains protein 1; SFMBT; SFMBT 1; Sfmbt1; SMBT1_HUMAN; Smr.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 98kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SFMBT1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition. [provided by RefSeq, Jun 2012]
Function:
Histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription. Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of associated corepressors and silencing of MYOD1 target genes. Part of the SLC complex in germ cells, where it may play a role during spermatogenesis.
Tissue Specificity:
Expressed in all cell lines and normal tissues tested, including the thymus.
Similarity:
Contains 4 MBT repeats.
Contains 1 SAM (sterile alpha motif) domain.
Database links:Entrez Gene: 51460Human
Entrez Gene: 54650Mouse
Entrez Gene: 58967Rat
Omim: 607319Human
SwissProt: Q9UHJ3Human
SwissProt: Q9JMD1Mouse
SwissProt: Q9JMD2Rat
Unigene: 343679Human
Unigene: 294662Mouse
Unigene: 14839Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.