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货号： bs-19609R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19609R-AP
- 英文名称
- Anti-SEC13L1/AP
- 中文名称
- 碱性磷酸酶（AP）标记的SEC13样蛋白1抗体
- 别 名
- D3S1231E; Npp 20; Npp20; Protein SEC13 homolog; SEC13 (S. cerevisiae) like 1; Sec13; SEC13 homolog (S. cerevisiae); SEC13 homolog; SEC13 like 1 (S. cerevisiae); SEC13 like 1 isoform; SEC13 like protein 1; SEC13 protein; SEC13 related protein; SEC13-like protein 1; SEC13-related protein; SEC13_HUMAN; SEC13R.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Rat, Cow, Chimpanzee,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 35kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SEC13L1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2008]
Function:
Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles.
Subunit:
At the nuclear pore: component of the Y-shaped Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex includes NUP160, NUP133, NUP107, NUP98, NUP85, NUP43, NUP37, SEH1 and SEC13. At the COPII coat complex: interacts with SEC31A and SEC31B. Within the GATOR complex, component of the GATOR2 subcomplex, made of MIOS, SEC13, SEH1L, WDR24 and WDR59. The GATOR complex strongly interacts with RRAGA/RRAGC and RRAGB/RRAGC heterodimers.
Subcellular Location:
Cytoplasmic vesicle; COPII-coated vesicle membrane. Endoplasmic reticulum membrane. Nucleus; nuclear pore complex. In interphase, localizes at both sides of the NPC.
Similarity:
Belongs to the WD repeat SEC13 family.
Contains 6 WD repeats.
Database links:Entrez Gene: 6396Human
Entrez Gene: 460167Chimpanzee
Entrez Gene: 607653Dog
Entrez Gene: 101153194Gorilla
Entrez Gene: 110379Mouse
Entrez Gene: 100451553Orangutan
Entrez Gene: 697339 Rhesus monkey
Omim: 600152Human
SwissProt: P55735Human
SwissProt: Q9D1M0Mouse
Unigene: 166924Human
Unigene: 29296Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.