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货号： bs-0770R 基本售价： 380.0 元 规格： 20ul
- 规格：20ul
- 价格：380.00元
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-0770R
- 英文名称
- SFTPA1
- 中文名称
- 肺表面活性蛋白A抗体
- 别 名
- SP-A; SFTPA2; SFTPA1; Surfactant Protein A; pulmonary surfactant-associated glycoprotein A; Pulmonary surfactant-associated protein A2 precursor; SP-A1; SP-A2; SP-A; PSP-A; PSPA; Alveolar proteinosis protein; 35 kDa pulmonary surfactant-associated protein; MGC133365; Pulmonary surfactant apoprotein; Pulmonary surfactant associated protein; SFTP1; SFTPA; SFTPA1B; SP A; SP A1; Surfactant pulmonary associated protein A1; PSPA; SPA2; SFTP1; SPAII; COLEC5; SFTPA2B; SFTA1_HUMAN; SFPA2_HUMAN; Pulmonary surfactant-associated protein A1; Pulmonary surfactant-associated protein A2.
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导 细胞表面分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- IHC-P=1:400-800 IHC-F=1:400-800 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 25kDa
- 细胞定位
- 细胞外基质 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SFTPA2/SFTPA1:23-120/248
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication. [provided by RefSeq, Sep 2009]
Function:
In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
Subunit:
Oligomeric complex of 6 set of homotrimers.
Subcellular Location:
Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
DISEASE:
Defects in SFTPA2 are a cause of pulmonary fibrosis idiopathic (IPF) [MIM:178500]. Pulmonary fibrosis is a lung disease characterized by shortness of breath, radiographically evident diffuse pulmonary infiltrates, and varying degrees of inflammation and fibrosis on biopsy. It results in acute lung injury with subsequent scarring and endstage lung disease.
Similarity:
Belongs to the SFTPA family.
Contains 1 C-type lectin domain.
Contains 1 collagen-like domain.
SWISS:
Q8IWL2
Gene ID:
653509
Database links:Entrez Gene: 610540 Dog
Entrez Gene: 653509 Human
Omim: 178630 Human
SwissProt: P06908 Dog
SwissProt: Q8IWL2 Human
Unigene: 535295 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肺泡表面活性物质A（SP-A）属糖结合蛋白家族,参与肺泡表面活性膜的形成和代谢,除在Ⅱ型细胞中强烈表达外，在细支气管、支气管上皮内也有灶性表达。
- 产品图片
Formalin-fixed and paraffin embedded mouse lung tissue labeled Anti-SP-A Polyclonal Antibody, Unconjugated (bs-0770R) at 1:2000, followed by conjugation to the secondary antibody and DAB staining
Tissue/cell: rat lung tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-SP-A Polyclonal Antibody, Unconjugated(bs-0770R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-SP-A Polyclonal Antibody, Unconjugated(bs-0770R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining