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货号： bs-8032R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-8032R
- 英文名称
- COLEC11
- 中文名称
- 凝集蛋白家族11抗体
- 别 名
- CL K1 IIb; Collectin kidney I; MGC129470; MGC129471; CL K1; CL K1 I; CL K1 II; CL K1 IIa; CLK1; COLEC 11; Collectin 11; Collectin kidney protein 1; Collectin sub family member 11; Collectin11; DKFZp686N1868; MGC3279; COL11_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 26kDa
- 细胞定位
- 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from Human COLEC11(kidney):122-200/271
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
COLEC11 is a 271 amino acid C-type lectin protein that contains a collagen-like domain and a carbohydrate recognition domain, and plays an important role in host-defense. COLEC11 binds to various sugars and LPS (lipopolysaccharides), which include fucose but does not bind to glucose, hnRNP, Beta-1,3-Gal-T3 or mannose. COLEC11 is ubiquitously expressed in most tissues with high expression in kidney, liver, fetal liver, small intestine, thymus, spinal cord, placenta, adrenal gland, pancreas and several cell lines. COLEC11 is a secreted protein and all alternatively spliced isoforms of COLEC11 have oligomeric structures created through disulfide bonding.
Function:
COLEC11 is a lectin that binds to various sugars: fucose > mannose. It does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine but binds to LPS.
Subcellular Location:
Secreted.
Tissue Specificity:
Ubiquitous.
DISEASE:
Defects in COLEC11 are the cause of 3MC syndrome type 2 (3MC2) [MIM:265050]. 3MC2 is an a disorder characterized by facial dysmorphism that includes hypertelorism, blepharophimosis, blepharoptosis and highly archedDE eyebrows, cleft lip and/or palate, craniosynostosis, learning disability and genital, limb and vesicorenal anomalies. The term 3MC syndrome includes Carnevale, Mingarelli, Malpuech, and Michels syndromes.
Similarity:
Belongs to the COLEC10/COLEC11 family.
Contains 1 C-type lectin domain.
Contains 1 collagen-like domain.
SWISS:
Q9BWP8
Gene ID:
78989
Database links:Entrez Gene: 78989 Human
Omim: 612502 Human
SwissProt: Q9BWP8 Human
Unigene: 32603 Human
Unigene: 735715 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.