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货号: bs-0014R 基本售价: 380.0 元 规格: 20ul
- 规格:20ul
- 价格:380.00元
- 规格:50ul
- 价格:780.00元
- 规格:100ul
- 价格:1380.00元
- 规格:200ul
- 价格:2200.00元
产品信息
- 产品编号
- bs-0014R
- 英文名称
- IGF 1
- 中文名称
- 胰岛素样生长因子1抗体
- 别 名
- IBP1; IGF 1; IGF I; IGF-1;IGF IA; IGF IB; IGF1; IGFI; IGFIA; Insulin like growth factor 1 (somatomedin C); Full=Insulin-like growth factor I; Insulin Like Growth Factor 1; Insulin like growth factor IA; Insulin like growth factor IB; Mechano growth factor; MGF; Mechano growth factor; MGF; Somatomedia C; Somatomedin C; IGF1_HUMAN. IGF-I;
- Specific References (6) | bs-0014R has been referenced in 6 publications.[IF=1.06] Baykara, B., et al. "Progesterone treatment decreases traumatic brain injury induced anxiety and is correlated with increased serum IGF-1 levels; prefrontal cortex, amygdala, hippocampus neuron density; and reduced serum corticosterone levels in immature rats." Biotechnic & Histochemistry 0 (2013): 1-8. Rat.PubMed:23480228[IF=1.06] Kiray, M., et al. "Effects of carbon dioxide exposure on early brain development in rats." Biotechnic & Histochemistry 0 (2014): 1-13. IHC-P ; Rat.PubMed:24476563[IF=0.48] Gabr, Hala, et al. "The effect of bone marrow‐derived mesenchymal stem cells on chemotherapy induced ovarian failure in albino rats." Microscopy Research and Technique (2016). IHC-P ; Rat.PubMed:27453009[IF=0.00] Liao, Wei-Tao, et al. "The effect of celastrol on learning and memory in diabetic rats after sevoflurane inhalation." (2016). IHC-P ; Rat.PubMed:0[IF=1.21] Müller, L., et al. "Different expression of leptin and IGF1 in the adult and prepubertal testis in dogs." Reproduction in Domestic Animals (2017). IHC-P ; Dog.PubMed:0[IF=1.80] Uysal, Nazan, et al. "Exercise increases leptin levels correlated with IGF-1 in hippocampus and prefrontal cortex of adolescent male and female rats." Journal of Chemical Neuroanatomy (2017). IHC-P ; Rat.PubMed:28179125
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 免疫学 发育生物学 信号转导 生长因子和激素 糖尿病
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 7.7/21kDa
- 细胞定位
- 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IGF-1:49-100/195
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
Function:
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.
Subcellular Location:
Secreted.
DISEASE:
Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.
Similarity:
Belongs to the insulin family.
SWISS:
P05019
Gene ID:
3479
Database links:Entrez Gene: 3479 Human
Omim: 147440 Human
SwissProt: P05019 Human
Unigene: 160562 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胰岛素样生长因子1(IGF-1)是一种生长调节激素,由肝分泌并入血液循环的中性多肽,具有调节生长和代谢、胰岛素样及促细胞分裂的活性,主要作用于成人。
- 产品图片
- Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IGF 1) Polyclonal Antibody, Unconjugated (bs-0014R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IGF 1) Polyclonal Antibody, Unconjugated (bs-0014R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.