GSK-199 hydrochloride
货号:
B1037-500 基本售价:
1340.0 元 规格:
500ug
产品信息
概述货号 | B1037-500 |
描述 | GSK-199 is a potent, reversible inhibitor of PAD4 (IC₅₀ = 200 nM. It binds to the low-calcium form of the enzyme and is selective for PAD4 over PAD1-3. It is less potent than the related PAD4 inhibitor GSK484 (IC₅₀ = 50 nM). GSK-199 can inhibit the citrullination of PAD4 target proteins and diminish the formation of neutrophil extracellular traps in mouse neutrophils. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
CAS号 | 1549811-53-1 |
外观 | Crystalline solid |