GSK-484 hydrochloride
货号:
B1035-500 基本售价:
1340.0 元 规格:
500ug
产品信息
概述货号 | B1035-500 |
描述 | GSK-484 is a potent and reversible inhibitor of PAD4 (Protein Arginine Deiminase 4) (IC₅₀ = 50 nM) that binds to the low-calcium form of the enzyme. It is selective for PAD4 over PAD1-3. GSK-484 blocks the citrullination of PAD4 target proteins in human neutrophils and inhibits the formation of neutrophil extracellular traps in both mouse and human neutrophils. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
CAS号 | 1652591-81-5 |
外观 | Crystalline solid |