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货号: bs-5789R-PE-Cy5 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-5789R-PE-Cy5
- 英文名称
- Anti-GPR39/PE-Cy5
- 中文名称
- PE-Cy5标记的G蛋白偶联受体39抗体
- 别 名
- GPCR GPR39; G protein coupled receptor GPR39; G Protein-Coupled Receptor 39; GPR 39; GPR39; GPR-39; MGC149541.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 细胞膜受体 G蛋白偶联受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 51kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GPR39.
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
GPCR39 is an integral membrane protein, which belongs to family 1 of G-protein coupled receptors. GPCR39 expression has been documented in human brain and peripheral tissues. ESTs have been isolated from human tissue libraries, including normal eye, brain, heart, melanocyte, uterus, vessel, cancerous brain, germ cell, kidney, and ovary.
Function:
Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death.
Subcellular Location:
Multi-pass membrane protein
Tissue Specificity:
Expressed in many tissues, including the stomach, intestine and hypothalamus.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:Entrez Gene: 2863Human
Entrez Gene: 71111Mouse
Entrez Gene: 288995Rat
Omim: 602886Human
SwissProt: O43194Human
SwissProt: Q5U431Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.