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货号： bs-2985R-PE-Cy5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2985R-PE-Cy5
- 英文名称
- Anti-ADM2/PE-Cy5
- 中文名称
- PE-Cy5标记的中介素抗体
- 别 名
- ADM2; IMD; Intermedin; Adrenomedullin-2; AM2; IMDL; IMDS; ADM2_HUMAN; Adrenomedullin 2; dJ579N16.4; FLJ21135; IMDL; Intermedin-long; Intermedin-short.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 5.2kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Intermedin
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a protein which is a member of the calcitonin-related hormones. The encoded protein is involved in maintaining homeostasis in many tissues, acting via CRLR/RAMP receptor (calcitonin receptor-like receptor/receptor activity-modifying protein) complexes. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011].
TISSUE SPECIFICITY:High expression detected in the submaxillary gland, kidney, stomach, and mesentery, followed by the pituitary, lung, pancreas, intestines, spleen, thymus and ovary. Expressed mainly in the intermediate lobe of the pituitary, with sporadic in the anterior lobe.
Function:
IMDL and IMDS may play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed in the esophagus, stomach, jejunum, ileum, ileocecum, ascending colon, transverse colon, descending colon and rectum. Expressed in myocardial cells of the heart, renal tubular cells, hypothalamus, and pituitary.
Similarity:
Belongs to the adrenomedullin family.
Database links:Entrez Gene: 79924 Human
Entrez Gene: 223780 Mouse
Entrez Gene: 399475 Rat
Omim: 608682 Human
SwissProt: Q7Z4H4 Human
SwissProt: Q7TNK8 Mouse
SwissProt: P61312 Rat
Unigene: 449099 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.