产品中心
当前位置：首页>产品中心Anti-ZFP161/PE-Cy3
货号： bs-18527R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18527R-PE-Cy3
- 英文名称
- Anti-ZFP161/PE-Cy3
- 中文名称
- PE-Cy3标记的锌指蛋白161抗体
- 别 名
- HZF5; MGC126126; ZBTB14; ZF161_HUMAN; ZF5; Zfp 161; Zfp-161; Zfp-5; Zfp161; Zinc finger and BTB domain containing protein 14; Zinc finger and BTB domain-containing protein 14; Zinc finger protein 161 homolog (mouse); Zinc finger protein 161 homolog; Zinc finger protein 478; Zinc finger protein 5; Zinc finger protein 5 homolog; Zinc finger protein homologous to Zfp161 in mouse; ZNF478.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 神经生物学 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 51kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZFP161
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
ZFP161 is a 449 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to distinct regions within the nucleus, ZFP161 functions both as a transcriptional repressor of Thymidine Kinase (TK) and c-Myc promoters and as a transcriptional activator of the dopamine transporter (DAT) promoter. ZFP161 contains one BTB (POZ) domain and five C2H2-type zinc fingers which direct its specific localization and nucleic acid binding, respectively. Defects in the gene encoding ZFP161 may be associated with holoprosencephaly type 4 (HPE4), a structural anomaly of the brain characterized by a flattened nasal tip with no visible septum, hypotelorism, lack of nasal bridge, ptosis of the left upper eyelid and, in some cases, infant death.
Function:
Transcriptional repressor of MYC and thymidine kinase promoters (By similarity). Transcriptional activator of the dopamine transporter (DAT), binding its promoter at the consensus sequence 5-CCTGCACAGTTCACGGA-3.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 1 BTB (POZ) domain.
Contains 5 C2H2-type zinc fingers.
Database links:Entrez Gene: 7541Human
Entrez Gene: 22666Mouse
Entrez Gene: 282825Rat
Omim: 602126Human
SwissProt: O43829Human
SwissProt: Q08376Mouse
Unigene: 592340Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.