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货号： bs-18521R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18521R-PE-Cy3
- 英文名称
- Anti-ZFAT/ZNF406/PE-Cy3
- 中文名称
- PE-Cy3标记的锌指蛋白406抗体
- 别 名
- AITD3; KIAA1485; MGC126815; MGC126817; ZFAT; ZFAT zinc finger 1; ZFAT_HUMAN; ZFAT1; zinc finger and AT hook domain containing; Zinc finger gene in AITD susceptibility region; zinc finger gene in autoimmune thyroid disease; Zinc finger protein 406; Zinc finger protein ZFAT; ZNF406;
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 淋巴细胞 t-淋巴细胞 b-淋巴细胞 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 139kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZFAT/ZNF
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]
Function:
May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated.
Subcellular Location:
Nucleus. Cytoplasm >cytosol.
Tissue Specificity:
Isoform 1 is strongly expressed in placenta, spleen, kidney, testis and peripheral blood leukocytes. Expressed in CD4+ and CD8+ T-cells, CD19+ B-cells and CB14+ monocytes. Isoform 3 is strongly expressed in placenta, ovary, tonsil, CD19+ B-cells and CD14+ monocytes.
Similarity:
Contains 19 C2H2-type zinc fingers.
Database links:Entrez Gene: 522282Cow
Entrez Gene: 482051Dog
Entrez Gene: 57623Human
Entrez Gene: 380993Mouse
Entrez Gene: 362925Rat
Omim: 610931Human
SwissProt: Q9P243Human
SwissProt: Q7TS63Mouse
Unigene: 446172Human
Unigene: 309526Mouse
Unigene: 33031Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.