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货号： bs-18177R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18177R-PE-Cy3
- 英文名称
- Anti-INTS4/PE-Cy3
- 中文名称
- PE-Cy3标记的INTS4蛋白抗体
- 别 名
- Int4; INT4_HUMAN; Integrator complex subunit 4; ints4; MGC16733; MST093; MSTP093; RGD1305036.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 108kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human INTS4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Function:
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the Integrator subunit 4 family.
Contains 8 HEAT repeats.
Database links:Entrez Gene: 100712822 Guinea pig
Entrez Gene: 92105Human
Entrez Gene: 101861Mouse
Entrez Gene: 100512005Pig
Entrez Gene: 100350308Rabbit
Entrez Gene: 308837Rat
Omim: 611348Human
SwissProt: Q96HW7Human
SwissProt: Q8CIM8Mouse
Unigene: 533723Human
Unigene: 27383Mouse
Unigene: 1948Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.