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货号： bs-6300R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6300R-PE-Cy3
- 英文名称
- Anti-TEM7R/PE-Cy3
- 中文名称
- PE-Cy3标记的肿瘤血管内皮标记相关蛋白质7抗体
- 别 名
- Tumor endothelial marker 7 related protein; Plexin domain containing 2; Plexin domain containing protein 2; Plexin domain-containing protein 2; PLXDC 2; plxdc2; PXDC2_HUMAN; TEM7R; Tumor endothelial marker 7-related protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 血管内皮细胞 肿瘤细胞生物标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 56kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TEM7R.
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
TEM7R also known as PLXDC2 is a 529 amino acid single-pass type I membrane protein containing one PSI domain and belonging to the plexin family. Localizing to membrane, TEM7R is expressed in endothelial cells of the stroma, as well as in limbs, lung buds, developing heart, spinal cord and dorsal root ganglia. TEM7R interacts with cortactin and may play a role in tumor angiogenesis. Existing as three alternatively spliced isoforms, the gene encoding TEM7R maps to human chromosome 10p12.31. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Function:
May play a role in tumor angiogenesis.
Subunit:
Interacts with CTTN.
Subcellular Location:
Membrane; Single-pass type I membrane protein
Tissue Specificity:
Expressed in the endothelial cells of the stroma but not in the endothelial cells of normal colonic tissue.
Similarity:
Belongs to the plexin family.
Contains 1 PSI domain.
Database links:Entrez Gene: 84898Human
Entrez Gene: 67448Mouse
Entrez Gene: 361282Rat
Omim: 606827Human
SwissProt: Q6UX71Human
SwissProt: Q9DC11Mouse
Unigene: 658134Human
Unigene: 313938Mouse
Unigene: 394655Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.