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货号： bs-3546R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3546R-Cy7
- 英文名称
- Anti-RIP2/Cy7
- 中文名称
- Cy7标记的受体结合丝氨酸苏氨酸激酶2抗体
- 别 名
- Receptor interacting protein 2; Receptor interacting serine threonine kinase 2; Receptor interacting serine/threonine protein kinase 2; RICK; RIP 2; RIP LIKE INTERACTING CLARP KINASE; RIPK 2; RIPK2; TNFRSF; CARD 3; CARD carrying kinase; CARD CONTAINING ICE ASSOCIATED KINASE; CARD containing IL 1 beta ICE kinase; CARD containing IL1 beta ICE kinase; CARD containing interleukin 1 beta converting enzyme (ICE) associated kinase; CARD containing interleukin 1 beta converting enzyme associated kinase; CARD3; CARDIAK; CCK; CLARP kinase; GIG 30; GIG30 ; Growth inhibiting gene 30; Receptor interacting protein (RIP) like interacting caspase like apoptosis regulatory protein (CLARP) kinase.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 细胞膜受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea Pig,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 60kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RIP2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
RIP2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
Function:
Activates pro-caspase-1 and pro-caspase-8. Potentiates CASP8-mediated apoptosis. Activates NF-kappa-B.
Subunit:
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.Contains 1 CARD domain.Contains 1 protein kinase domain.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Detected in heart, brain, placenta, lung, peripheral blood leukocytes, spleen, kidney, testis, prostate, pancreas and lymph node.
Post-translational modifications:
Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.Ubiquitinated; undergoes Lys-63-linked polyubiquitination catalyzed by ITCH.
Similarity:
Belongs to the protein kinase superfamily.
TKL Ser/Thr protein kinase family.
Contains 1 CARD domain.
Contains 1 protein kinase domain.
Database links:Entrez Gene: 8767Human
Entrez Gene: 192656Mouse
Entrez Gene: 362491Rat
Omim: 603455Human
SwissProt: O43353Human
SwissProt: P58801Mouse
Unigene: 103755Human
Unigene: 112765Mouse
Unigene: 102179Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
受体结合丝氨酸苏氨酸激酶2又称受体相互作用蛋白2。