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货号： bs-3628R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3628R-Cy7
- 英文名称
- Anti-PRL3/Cy7
- 中文名称
- Cy7标记的磷酸酯酶3蛋白抗体
- 别 名
- PRL-R;Potentially prenylated protein tyrosine phosphatase; PRL 3; PRL R; PRLR: PRL3; PRLR; Protein tyrosine phosphatase 4a3; PTP 4A3: PTP4A3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 信号转导 转录调节因子 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep, Guinea Pig, Danio
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 19kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PRL3/PTP4A3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
PTP4A3 protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. It enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. It may be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. PTP4A3 interacts with tubulin. It belongs to the protein tyrosine phosphatase family. It is mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. It is consistently overexpressed in colon cancer metastasis.
Subunit:
Interacts with tubulin.
Subcellular Location:
Cell membrane. Early endosome.
Tissue Specificity:
Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis.
Similarity:
Belongs to the protein-tyrosine phosphatase family.
Contains 1 tyrosine-protein phosphatase domain.
Database links:Entrez Gene: 11156 Human
Entrez Gene: 19245 Mouse
Entrez Gene: 362930 Rat
Entrez Gene: 406460 Zebrafish
Omim: 606449 Human
SwissProt: O75365 Human
SwissProt: Q9D658 Mouse
SwissProt: Q78EG7 Rat
SwissProt: Q6NX92 Zebrafish
Unigene: 43666 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.