产品中心
当前位置：首页>产品中心Anti-BRN3A/Cy7
货号： bs-3669R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3669R-Cy7
- 英文名称
- Anti-BRN3A/Cy7
- 中文名称
- Cy7标记的转录因子Brn3蛋白抗体
- 别 名
- Brain specific homeobox/POU domain protein 3A; Brn 3.0; BRN 3A; Brn3; Homeobox/POU domain protein RDC 1; Homeobox/POU domain protein RDC1; Oct T1; OctT1; POU Domain Class 4 Transcription Factor 1; POU4F1; RDC 1; RDC1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 免疫学 神经生物学 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 43kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human BRN3A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012].
Function:
Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons.
Subcellular Location:
Nucleus.
Tissue Specificity:
Brain. Seems to be specific to the retina. Present in the developing brain, spinal cord and eye.
DISEASE:
Expression peaks early in embryogenesis (day 13.5) and is undetectable 14 days after birth.
Similarity:
Belongs to the POU transcription factor family. Class-4 subfamily.
Contains 1 homeobox DNA-binding domain.
Contains 1 POU-specific domain.
Database links:Entrez Gene: 5457Human
Entrez Gene: 18996Mouse
Entrez Gene: 114503Rat
Omim: 601632Human
SwissProt: Q01851Human
SwissProt: P17208Mouse
SwissProt: P20266Rat
Unigene: 654522Human
Unigene: 246550Mouse
Unigene: 232568Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子Brn3可能直接参与对轴突和树突生长能力的调控。