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货号： bs-3671R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3671R-Cy7
- 英文名称
- Anti-BMP6/Cy7
- 中文名称
- Cy7标记的骨形态发生蛋白6抗体
- 别 名
- Bone Morphogenic Protein 6; Decapentaplegic vegetal related; DVR6; BMP 6; BMP-6; TGFB related vegetal related growth factor; Transforming growth factor beta; Vegetal related (TGFB related) cytokine; Vg related sequence; VGR1; BMP6_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 生长因子和激素 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 16/56kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human BMP6
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq].
Function:
Induces cartilage and bone formation.
Subunit:
Interacts with SOSTDC1.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed in the lung. Low levels seen in the kidney.
Similarity:
Belongs to the TGF-beta family.
Database links:Entrez Gene: 654 Human
Entrez Gene: 12161 Mouse
Entrez Gene: 25644 Rat
Omim: 112266 Human
SwissProt: P22004 Human
SwissProt: P20722 Mouse
SwissProt: Q04906 Rat
Unigene: 285671 Human
Unigene: 385759 Mouse
Unigene: 40476 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
BMP6具有诱导软骨内骨化,对刺激骨折愈合和异位骨形成的活性的作用，近年来经研究发现，BMP6与肾胚胎和泌尿系统的发育有关，并参与肝脏生长和分化以及角质细胞形成分化和神经组织的发育调控。