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货号： bs-3675R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3675R-Cy7
- 英文名称
- Anti-R-cadherin/Cy7
- 中文名称
- Cy7标记的R-钙粘附分子抗体
- 别 名
- Cadherin 4; Cadherin4; Cadherin-4 CDH4; R CAD; Retinal Cadherin.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 激酶和磷酸酶 细胞粘附分子 糖蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Cow, Horse,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 81kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human R-cadherin(423-475aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Cadherins constitute a superfamily of calcium-dependent intercellular adhesion molecules and are thought to play a role in cell recognition and segregation, morphogenetic regulation, and tumor suppression. R Cadherin is expressed mainly in the brain but is also found in other tissues.
Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed mainly in brain but also found in other tissues.
Similarity:
Contains 5 cadherin domains.
Database links:Entrez Gene: 1002 Human
Entrez Gene: 12561 Mouse
Entrez Gene: 114588 Rat
Omim: 603006 Human
SwissProt: P55283 Human
SwissProt: P39038 Mouse
SwissProt: Q80ZV4 Mouse
SwissProt: Q63149 Rat
Unigene: 473231 Human
Unigene: 598638 Human
Unigene: 184711 Mouse
Unigene: 382094 Mouse
Unigene: 392073 Mouse
Unigene: 214089 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
R-钙粘附分子,是依赖钙离子的细胞间糖蛋白粘附分子的一种，主要是参与细胞间同源性粘附、调控和介导细胞间相互反应，在肿瘤的迁移、分化中起到一定的作用。在脑组织中表达外，其他组织中已有定位。