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货号： bs-3677R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3677R-Cy7
- 英文名称
- Anti-CYP8A1/Cy7
- 中文名称
- Cy7标记的前列环素合成酶抗体
- 别 名
- CYP8; CYP8A1; Cytochrome P450, family 8, subfamily A, polypeptide 1; PGIS; Prostacyclin synthase; Prostaglandin I2 (prostacyclin) synthase; Prostaglandin I2 synthase; PTGI.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 免疫学 糖尿病 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 55kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CYP8A1/PTGIS
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.
Subcellular Location:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity:
Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate.
Similarity:
Belongs to the cytochrome P450 family.
Database links:Entrez Gene: 5740 Human
Entrez Gene: 19223 Mouse
Entrez Gene: 25527 Rat
Omim: 601699 Human
SwissProt: Q29626 Cow
SwissProt: Q16647 Human
SwissProt: O35074 Mouse
SwissProt: Q62969 Rat
Unigene: 5247 Cow
Unigene: 302085 Human
Unigene: 2339 Mouse
Unigene: 73051 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.