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货号： bs-4039R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4039R-Cy7
- 英文名称
- Anti-SLC37A4/Cy7
- 中文名称
- Cy7标记的葡萄糖-6磷酸转运蛋白抗体
- 别 名
- G6PT2; GSD1b; GSD1c; GSD1d; TRG19; G6PT1; G6PT3; Glucose-5-phosphate transporter; Glucose-6-phosphatase, transport (glucose) protein 3 antibody; Glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1; Glucose-6-phosphatase, transport (phosphate/pyrophosphate) protein 2; Glucose-6-phosphate translocase; Glucose-6-phosphate transporter 1; Microsomal glucose-6-phosphate transporter; Solute carrier family 37 (glucose-6-phosphate transporter), member 4; MGC15729; PRO0685; G6PT1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 转录调节因子 转运蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 46kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human G6PT2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
SLC37A4 transports glucose-6-phosphate from the cytoplasm to the lumen of the endoplasmic reticulum. It forms a complex with glucose-6-phosphatase which is responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.
Function:
Transports glucose-6-phosphate from the cytoplasm to the lumen of the endoplasmic reticulum. Forms with glucose-6-phosphatase the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.
Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Specificity:
Mostly expressed in liver and kidney
DISEASE:
Defects in SLC37A4 are the cause of glycogen storage disease type 1B (GSD1B) [MIM:232220]. GSD1B is a metabolic disorder characterized by impairment of terminal steps of glycogenolysis and gluconeogenesis. GSD1 patients manifest a wide range of clinical symptoms and biochemical abnormalities, including hypoglycemia, severe hepatomegaly due to excessive accumulation of glycogen, kidney enlargement, growth retardation, lactic acidemia, hyperlipidemia, and hyperuricemia. GSD1B patients also present a tendency towards infections associated with neutropenia, relapsing aphthous gingivostomatitis, and inflammatory bowel disease.
Defects in SLC37A4 are the cause of glycogen storage disease type 1C (GSD1C) [MIM:232240].
Defects in SLC37A4 are the cause of glycogen storage disease type 1D (GSD1D) [MIM:232240].
Similarity:
Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
Database links:Entrez Gene: 2542Human
Entrez Gene: 14385Mouse
Entrez Gene: 29573Rat
Omim: 602671Human
SwissProt: O43826Human
Unigene: 719203Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.