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货号: bs-3852R-Cy7 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-3852R-Cy7
- 英文名称
- Anti-TNFRSF19/Cy7
- 中文名称
- Cy7标记的肿瘤坏死因子配体超家族成员19抗体
- 别 名
- TROY; TAJ alpha; TAJ; TNFRSF 19; TNFRSF19; Tnfrsf20; Toxicity and JNK inducer; TRADE; Tumor necrosis factor receptor superfamily member 19.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 生长因子和激素 转录调节因子 细胞表面分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, G
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 43kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TROY C-terminus
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
TROY is a member of the TNF receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate the JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Subunit:
Associates with TRAF1, TRAF2, TRAF3 and TRAF5. Interacts with LINGO1.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.
Similarity:
Contains 3 TNFR-Cys repeats.
Database links:Entrez Gene: 55504 Human
Entrez Gene: 29820 Mouse
Omim: 606122 Human
SwissProt: Q9NS68 Human
SwissProt: Q9JLL3 Mouse
Unigene: 149168 Human
Unigene: 730848 Human
Unigene: 281356 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.