产品中心
当前位置：首页>产品中心Anti-CYP7A1/Cy7
货号： bs-2399R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2399R-Cy7
- 英文名称
- Anti-CYP7A1/Cy7
- 中文名称
- Cy7标记的细胞色素P450 7A1抗体/胆固醇7a羟化酶抗体
- 别 名
- Cholesterol 7 alpha hydroxylase; Cholesterol 7 alpha monooxygenase; cholesterol 7 alpha-monooxygenase; Cholesterol 7-alpha-hydroxylase; Cholesterol 7-alpha-monooxygenase; CP7A; CYP 7; CYP7; CYPVII; Cytochrome P450 7A1; cytochrome P450, family 7, subfamily A, polypeptide 1; Cytochrome P450, subfamily VIIA (cholesterol 7 alpha monooxygenase); CP7A1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 生长因子和激素 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Rabbit, Guinea Pig, ,G
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 55kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CYP7A1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010].
Function:
Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
Subcellular Location:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity:
Detected in liver.
Similarity:
Belongs to the cytochrome P450 family.
Database links:Entrez Gene: 1581Human
Entrez Gene: 13122Mouse
Entrez Gene: 25428Rat
Omim: 118455Human
SwissProt: P22680Human
SwissProt: Q64505Mouse
SwissProt: P18125Rat
Unigene: 1644Human
Unigene: 57029Mouse
Unigene: 10737Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.