产品中心
当前位置：首页>产品中心Anti-GABARAPL2/Cy7
货号： bs-4014R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4014R-Cy7
- 英文名称
- Anti-GABARAPL2/Cy7
- 中文名称
- Cy7标记的G1氨基丁酸A型受体相似蛋白2抗体
- 别 名
- ATG 8; ATG8; FLC 3A; FLC3A; GABA(A) receptor associated protein like 2; Gamma aminobutyric acid receptor associated protein like 2; Ganglioside expression factor 2; GATE 16; GATE16; General protein transport factor p16; MAP1 light chain 3 related protein; GABA(A) receptor-associated protein-like 2; Gabarapl2; Gamma-aminobutyric acid receptor-associated protein-like 2; GATE-16; GBRL2_HUMAN; GEF 2; GEF-2; GEF2; Golgi-associated ATPase enhancer of 16 kDa; MAP1 light chain 3-related protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 染色质和核信号 神经生物学 细胞凋亡
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Cow, Rabbit,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 14kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GABARAPL2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing (1). GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC (2,3). In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein) (4-6). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton (6). The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex (6).
Function:
Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.
Subcellular Location:
Golgi apparatus.
Tissue Specificity:
Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the MAP1 LC3 family.
Database links:Entrez Gene: 11345Human
Entrez Gene: 93739Mouse
Entrez Gene: 100359937Rat
Entrez Gene: 64670Rat
Omim: 607452Human
SwissProt: P60520Human
SwissProt: P60521Mouse
SwissProt: P60522Rat
Unigene: 461379Human
Unigene: 371666Mouse
Unigene: 120952Rat
Unigene: 64537Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GABAA受体相关蛋白相似蛋白2；GABA受体A型相关蛋白样2