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货号： bs-3895R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3895R-Cy7
- 英文名称
- Anti-SOD3/Cy7
- 中文名称
- Cy7标记的超氧化物歧化酶3抗体
- 别 名
- EC-SOD; Superoxide Dismutase 3; ALS; ALS1; Cu/Zn superoxide dismutase; EC SOD; Extracellular superoxide dismutase [Cu Zn]; Extracellular superoxide dismutase; Extracellular superoxide dismutase precursor; Homodimer; Indophenoloxidase A; IPOA; Mn superoxide dismutase; SOD 3; SOD; SOD soluble; SOD2; SOD3; Superoxide dismutase 3 extracellular; Superoxide dismutase cystolic; SODE_HUMAN; extracellular superoxide dismutase isoform 1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 染色质和核信号 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 24kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SOD3 extracellular superoxide dismutase isoform 1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. [provided by RefSeq, Jul 2008]
Function:
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
Subunit:
Homotetramer.
Subcellular Location:
Secreted, extracellular space. Note=99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium.
Tissue Specificity:
Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.
Similarity:
Belongs to the Cu-Zn superoxide dismutase family.
Database links:Entrez Gene: 6649 Human
Entrez Gene: 20657 Mouse
Entrez Gene: 25352 Rat
Omim: 185490 Human
SwissProt: P08294 Human
SwissProt: O09164 Mouse
SwissProt: Q08420 Rat
Unigene: 2420 Human
Unigene: 2407 Mouse
Unigene: 10358 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.