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货号： bs-3933R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3933R-Cy7
- 英文名称
- Anti-CACH6/Cav2.3/Cy7
- 中文名称
- Cy7标记的L型钙通道蛋白a1亚型6抗体
- 别 名
- BII; Brain calcium channel II; CAC 1E; CAC1E; CACH 6; CACH6; CACNA1E; Cacnl1 a6; CACNL1A6; Calcium channel, L type, alpha 1 polypeptide, isoform 6; calcium channel, R type; Cav 2.3; Cchra 1; Cchra1; Voltage dependent R type calcium channel subunit alpha 1E; Voltage gated calcium channel subunit alpha Cav2.3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 神经生物学 信号转导 通道蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 262kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Cav23
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the "high voltage-activated" group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in neuronal tissues and in kidney.
Similarity:
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1E subfamily.
Contains 1 EF-hand domain.
Database links:Entrez Gene: 12290 Mouse
SwissProt: Q61290 Mouse
SwissProt: Q07652 Rat
Unigene: 267517 Mouse
Unigene: 10742 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.