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货号： bs-3940R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3940R-Cy7
- 英文名称
- Anti-G protein beta 4/Cy7
- 中文名称
- Cy7标记的G蛋白β4抗体/鸟嘌呤核苷酸结合蛋白β亚基4
- 别 名
- G protein beta 4 subunit; GNB 4; GNB4; Guanine nucleotide binding protein (G protein) beta polypeptide 4; Guanine nucleotide binding protein beta 4 subunit; Guanine nucleotide binding protein beta polypeptide 4; Guanine nucleotide binding protein beta subunit 4; Guanine nucleotide binding protein subunit beta 4; Transducin beta chain 4; GBB4_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 转录调节因子 结合蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 37kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human G protein beta 4 (52-90aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Guanine nucleotide binding proteins (G proteins) are membrane associated, heterotrimeric proteins composed of three subunits: alpha, beta and gamma. The G protein beta subunit assumes a barrel shaped beta propeller structure containing WD40 repeats preceded by an N terminal alpha helix. The beta subunit forms a stable dimer with the gamma subunit. The alpha subunit only contacts the beta subunit in the dimer, lying on the opposite face from the gamma subunit.G proteins and their receptors (GPCRs) regulate systems as diverse as sensory perception, cell growth and hormonal regulation.
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subunit:
G proteins are composed of 3 units, alpha, beta and gamma.
Tissue Specificity:
Strongly expressed in lung and placenta, whereas it is weakly expressed in brain and heart.
Similarity:
Belongs to the WD repeat G protein beta family.
Contains 7 WD repeats.
Database links:Entrez Gene: 59345 Human
Entrez Gene: 14696 Mouse
Entrez Gene: 294962 Rat
Omim: 610863 Human
SwissProt: Q9HAV0 Human
SwissProt: P29387 Mouse
SwissProt: Q3THF3 Mouse
SwissProt: Q3TY18 Mouse
SwissProt: Q3U2F9 Mouse
SwissProt: O35353 Rat
SwissProt: Q4V8I8 Rat
Unigene: 173030 Human
Unigene: 139192 Mouse
Unigene: 10844 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.