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货号： bs-4026R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4026R-Cy7
- 英文名称
- Anti-ALDOB/Cy7
- 中文名称
- Cy7标记的醛缩酶2抗体
- 别 名
- ALDB; ALDO B; ALDO2; ALDOB; ALDOB_HUMAN; Aldolase 2; Aldolase B; Aldolase B fructose bisphosphate; Aldolase2; AldolaseB; EC 4.1.2.13; Fructose bisphosphate aldolase B; Fructose-bisphosphate aldolase B; Liver type aldolase; Liver-type aldolase; MS1077.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 39kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ALDOB
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
ALDOB is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Defects in ALDOB cause hereditary fructose intolerance.
Subunit:
Homotetramer.
DISEASE:
Hereditary fructose intolerance (HFI) [MIM:229600]: Autosomal recessive disease that results in an inability to metabolize fructose and related sugars. Complete exclusion of fructose results in dramatic recovery; however, if not treated properly, HFI subjects suffer episodes of hypoglycemia, general ill condition, and risk of death the remainder of life. Note=The disease is caused by mutations affecting the gene represented in this entry.
Similarity:
Belongs to the class I fructose-bisphosphate aldolase family.
Database links:Entrez Gene: 229 Human
Entrez Gene: 230163 Mouse
Entrez Gene: 24190 Rat
Omim: 612724 Human
SwissProt: P05062 Human
SwissProt: Q91Y97 Mouse
SwissProt: P00884 Rat
Unigene: 530274 Human
Unigene: 482116 Mouse
Unigene: 98207 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
醛缩酶（ALD）与机体能量代谢密切相关。醛缩酶含量比较丰富，分布也叫广泛，醛缩酶B是一种与糖酵解有关的酶类，在人类和哺乳动物组织中存在3种醛缩酶同工酶，即A(肌型)，B(肝型)和C（脑型）。其中B型基因定位于q13-q32，属胞浆酶。研究表明，ALDOB在肝细胞癌发展过程中呈现出一定规律的变化，与原发性肝癌有关。ALDOB蛋白主要定位于胞浆。