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货号： bs-3988R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3988R-Cy7
- 英文名称
- Anti-GLUT5/Cy7
- 中文名称
- Cy7标记的葡萄糖转运蛋白5抗体
- 别 名
- GLUT-5; GLUT 5; Glucose Transporter 5 GLUT5; Glucose Transporter 5 Facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5 small intestine; SLC2A5; Solute carrier family 2; small intestine.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导 转录调节因子 转运蛋白 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Rabbit,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 55kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GLUT5
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Ten types of glucose/fructose transport carrier proteins designated as Glut 1-10 facilitate glucose/fructose transport across the cell membrane. Molecular cloning of glucose transporters have identified a family of closely related genes that encodes at least 7 proteins exhibiting high degree of amino acid homology (45%-65%) all in the molecular weight range of 40-60 kDa. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers. Majority of the differences in sequence homology in Glut proteins occur at 4 hydrophilic domains that may play a role in distinct tissue-specific pattern of expression and targeting. All Glut proteins are glycosylated at or near the C-terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes as in blood brain barrier and blood testis barriers.
Glut 5 seems to function primarily as a fructose transporter; it is expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose
Function:
Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.
Similarity:
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
Database links:Entrez Gene: 6518 Human
Entrez Gene: 56485 Mouse
Entrez Gene: 65197 Rat
Omim: 138230 Human
SwissProt: P22732 Human
SwissProt: Q9WV38 Mouse
SwissProt: P43427 Rat
Unigene: 530003 Human
Unigene: 260220 Mouse
Unigene: 10900 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.