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货号： bs-4040R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4040R-Cy7
- 英文名称
- Anti-IL18BP/Cy7
- 中文名称
- Cy7标记的白细胞介素18结合蛋白抗体
- 别 名
- IL18 BP; IL18 BPa; IL18BP; IL18BPa; Interleukin 18 binding protein; Tadekinig alfa; I18BP_HUMAN; IL-18BP; Interleukin-18-binding protein
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 转录调节因子 结合蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 18kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IL18BP
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
IL18 binding protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18 induced IFN gamma production. It is constitutively expressed and secreted in mononuclear cells and can be enhanced by IFN gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn disease. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Function:
Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
Subcellular Location:
Secreted.
Tissue Specificity:
Strongly expressed in heart, lung, placenta and spleen.
Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Database links:Entrez Gene: 10068 Human
Entrez Gene: 84388 Rat
Omim: 604113 Human
SwissProt: O95998 Human
Unigene: 591967 Human
Unigene: 20083 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.