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货号： bs-5020R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-5020R-Cy7
- 英文名称
- Anti-SOAT2/Cy7
- 中文名称
- Cy7标记的胆固醇酰基转移酶2抗体
- 别 名
- Acat2; acetoacetyl CoA thiolase; acetoacetyl Coenzyme A thiolase; Acetyl CoA acetyltransferase; Acetyl CoA transferase like protein; acetyl Coenzyme A acetyltransferase 2; Acetyl-CoA acetyltransferase; Acetyl-CoA transferase-like protein; Acyl Coenzyme A cholesterol acyltransferase 2; Cytosolic acetoacetyl-CoA thiolase; cytosolic; SOAT2; SOAT2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 免疫学 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 60kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ACAT2 (355-400aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Acetyl-Coenzyme A acetyltransferase 2 is an enzyme involved in lipid metabolism. Reported patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.
Function:
Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
Subunit:
May form homo- or heterodimers (By similarity).
Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Similarity:
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
Database links:Entrez Gene: 8435 Human
Omim: 601311 Human
SwissProt: O75908 Human
Unigene: 20580 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.