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货号： bs-2397R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2397R-Cy7
- 英文名称
- Anti-Endothelial lipase/Cy7
- 中文名称
- Cy7标记的内皮脂肪酶抗体
- 别 名
- LIPG; EC 3.1.1.3; EDL; EL; Endothelial cell-derived lipase; Endothelial lipase; Endothelial lipase precursor; Lipase endothelial; LIPE_HUMAN; LIPG; Lipoprotein lipase H; PL; PRO719.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 心血管 细胞生物 免疫学 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 克 隆 号
- 55kDa
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 55kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Endothelial lipase
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. [provided by RefSeq, Jul 2008].
Function:
Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin.
Subunit:
Head to tail homodimer.
Subcellular Location:
Secreted.
Tissue Specificity:
High level of expression in the liver, placenta, lung, thyroid, kidney, testis and in the corpus luteum of the ovary. Expressed also in coronary artery endothelial cells, umbilical vein endothelial cells and in hepatocytes and osteosarcoma cell lines. Not detected in heart, brain and muscle.
Similarity:
Belongs to the AB hydrolase superfamily. Lipase family.
Contains 1 PLAT domain.
Database links:Entrez Gene: 9388 Human
Entrez Gene: 291437 Rat
Omim: 603684 Human
SwissProt: Q9Y5X9 Human
SwissProt: Q8VBX1 Rat
Unigene: 465102 Human
Unigene: 199051 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
EL被确定为甘油三酯脂肪酶家族的新成员，由于EL是由血管内皮细胞合成和分泌，因此被命名为内皮脂肪酶，相应的基因命名为内皮脂肪酶基因(endothelial lipase gene，LIPG)。EL也是一种分泌型蛋白，由483个氨基酸组成，分子量约55kD，在人体多种组织中都有表达：冠状动脉、胎盘、甲状腺、肝脏、肺脏、肾脏、睾丸和卵巢等组织中都可发现。