产品中心
当前位置：首页>产品中心Anti-CKLF/Cy7
货号： bs-2394R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2394R-Cy7
- 英文名称
- Anti-CKLF/Cy7
- 中文名称
- Cy7标记的趋化素样蛋白抗体
- 别 名
- C32; Chemokine-like factor; chemokine-like factor 1; chemokine-like factor 2; chemokine-like factor 3; chemokine-like factor 4; CKLF_HUMAN; CKLF1; CKLF2; CKLF3; CKLF4; CKLFSF2; HSPC224; transmembrane proteolipid; UCK-1; UCK1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 细胞分化 淋巴细胞
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Rabbit,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 17kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CKLF
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).[provided by RefSeq, Feb 2011]
Function:
May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10.
Isoform 1 has chemotactic response in rat monocytes, neutrophils, and lymphocytes.
Subcellular Location:
Isoform 1: Secreted.
Isoform 2: Membrane; Multi-pass membrane protein.
Isoform 4: Membrane; Multi-pass membrane protein.
Tissue Specificity:
Isoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skeletal muscle, liver, thymus colon, prostate and fetal spleen and liver.
Similarity:
Belongs to the chemokine-like factor family.
Contains 1 MARVEL domain.
Database links:Entrez Gene: 51192 Human
Entrez Gene: 75458 Mouse
Entrez Gene: 245978 Rat
Omim: 607885 Human
SwissProt: Q9UBR5 Human
SwissProt: Q9DAS1 Mouse
SwissProt: Q9JK79 Rat
Unigene: 15159 Human
Unigene: 81197 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CKLF（趋化素样因子）是人类趋化素样因子超家族CKLFSF（Chemokine-like Factor Super Family，趋化素样因子超家族）中的一员，趋化因子能使细胞发生趋化运动的小分子细胞因子。趋化因子结构和功能比较相似,分子量多在10-20kDa之间,对嗜中性粒细胞、淋巴细胞、单核细胞等多种细胞有趋化活性。